Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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MMP1334Solute-binding protein/glutamate receptor:ATP/GTP-binding site motif A (P-loop):GTP-binding protein, HSR1-related:GTP-binding. (384 aa)    
Predicted Functional Partners:
MMP0901
ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain.
  
 
 0.978
MMP0596
RNA 2'-O-methyl modification protein (NOP5/NOP56); Citation: Hickey, A.J., Macario, A.J.L., and Conway de Macario, E. Gene 253:77-85,2000.
  
 
 0.950
MMP1126
Putative proliferating-cell nucleolar antigen; Citation: Cancer Commun. 1989;1(4):243-51, Oncogene (1997) 14: 629-640, Genes to Cells (2002) 7: 911-922; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
 
 0.936
rps8e
SSU ribosomal protein S8E.
   
 
 0.932
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
 
 0.930
rpmD
LSU ribosomal protein L30P.
   
 
 0.927
rlmE
23 S ribosomal RNA methyltransferase related; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
   
 
 0.922
flpA-2
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
 0.920
MMP0247
Conserved hypothetical archaeal protein; Probably involved in the biogenesis of the ribosome.
   
 
 0.912
cbf5
Pseudouridine syntase related protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
 
 
 0.911
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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