Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1350Conserved hypothetical protein. (437 aa)    
Predicted Functional Partners:
MMP1351
N-acetyltransferase domain-containing protein; Unnamed protein product.
  
    0.957
MMP1348
Conserved hypothetical protein; Belongs to the UPF0292 family.
  
    0.784
nadE
NAD+ synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
    0.766
MMP0412
Protein of unknown function UPF0004:Deoxyribonuclease/rho motif-related TRAM.
 
    0.676
thi4
NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
 
     0.586
MMP1353
Conserved hypothetical protein.
 
    0.560
secD
SecD/SecF/SecDF export membrane protein; Involved in protein export.
 
   
 0.495
MMP1343
Conserved hypothetical protein.
  
    0.476
HMmB
Archaeal histone B; Citation: Trends in Genetics (2002) 18: 621-626, PNAS (1994) 91: 12624-12628.
       0.459
MMP1554
Conserved hypothetical archaeal protein.
 
     0.450
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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