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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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MMP1355Bacterial transferase hexapeptide repeat. (226 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis protein:THUMP domain; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
    0.880
MMP1343
Conserved hypothetical protein.
  
  
 0.661
uppS
Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
  
 0.578
MMP0176
CDC48 cell division cycle protein family member; ATP/GTP-binding site motif A (P-loop); Citation: Mol. Gen. Genet. (1999) 262: 559-567, Cell (1995) 82: 885-893.
  
 
 0.574
MMP1353
Conserved hypothetical protein.
  
    0.565
MMP1348
Conserved hypothetical protein; Belongs to the UPF0292 family.
  
 
 0.546
nadE
NAD+ synthase related protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.499
thi4
NAD binding site:TonB-dependent receptor protein:Thiamine biosynthesis Thi4 protein; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
  
  
 0.478
MMP1351
N-acetyltransferase domain-containing protein; Unnamed protein product.
  
    0.447
mdh
Malate dehydrogenase, MDHII (NADP+-dependent); Catalyzes the reversible oxidation of malate to oxaloacetate.
 
 
 0.432
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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