Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1378Hypothetical protein. (58 aa)    
Predicted Functional Partners:
cofH-2
FO synthase, subunit CofH; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine.
   
  
 0.661
frcB
Coenzyme F420-reducing hydrogenase subunit beta; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A.
   
  
 0.654
cofH
FO synthase, subunit CofH; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine.
      
 0.631
fwdB
Tungsten containing formylmethanofuran dehydrogenase subunit B; Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.
   
  
 0.518
hdrA-2
Heterodisulfide reductase, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
  
 0.506
hdrA
Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
  
 0.471
MMP1377
Conserved hypothetical protein.
       0.450
MMP1376
Conserved hypothetical protein.
  
    0.449
fdhC
Formate transporter.
      
 0.427
MMP1304
Response regulator receiver.
   
  
 0.401
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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