STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rplELSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (181 aa)    
Predicted Functional Partners:
rpl18a
Ribosomal LX protein.
   
 0.999
rpl31e
Ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family.
   
 0.999
rpl21e
Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 0.999
rpl40e
LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.999
rps19e
Ribosomal protein S19E (S16A); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
   
 
 0.999
rpl37ae
Ribosomal L37ae protein; Binds to the 23S rRNA.
 
 
 0.999
P1
LSU ribosomal protein L12A; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.
   
 0.999
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.999
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
 0.999
rpl15
LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family.
  
 0.999
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.