Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1468Conserved hypothetical protein; Catalyzes the cleavage of L-cysteine to form 2-aminoprop-2- enoate and sulfide. The former then spontaneously hydrolyzes to pyruvate and NH(3). May be responsible for the production of sulfide required for the biosynthesis of iron-sulfur centers in this archaea. (396 aa)    
Predicted Functional Partners:
MMP0739
Asp/Glu racemase:Aspartate racemase.
     
  0.900
MMP1072
Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9.
     
  0.900
MMP1606
Flavoprotein:DNA/pantothenate metabolism flavoprotein.
     
  0.800
rpsJ
SSU ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
      
 0.667
ehbA
Conserved hypothetical protein; Citation: Tersteegen A, Hedderich R Eur. J. Biochem. 264, 930 (1999).
  
    0.664
trpF
N-(5'phosphoribosyl)anthranilate isomerase; Citation: Sterner R, Kleemann GR, Szadkowski H, Lustig A, Hennig M, Kirschner K. (1996). Protein Sci. 5:2000-8; Belongs to the TrpF family.
       0.617
MMP1571
Conserved hypothetical archaeal protein.
  
    0.406
pdfA
Prefoldin alpha subunit (GimC alpha subunit); Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
       0.405
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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