Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP1475Hypothetical protein. (277 aa)    
Predicted Functional Partners:
MMP0852
Conserved hypothetical protein.
   
    0.804
MMP1293
Glycosyl transferase, group 1.
   
    0.630
MMP1174
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
    0.606
MMP0914
Conserved hypothetical archaeal protein.
   
    0.601
MMP1476
Conserved hypothetical archaeal protein.
       0.551
MMP0963
Aquaporin related.
   
    0.444
cbiA
Cobyrinic acid a,c-diamide synthase.
  
    0.439
cbiA-2
Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA.
  
    0.439
MMP0546
Protein of unknown function DUF51.
   
    0.419
hdrB1
Heterosulfide reductase, subunit B1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
    0.408
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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