STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiA-2Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA. (349 aa)    
Predicted Functional Partners:
cbiA
Cobyrinic acid a,c-diamide synthase.
 
 0.999
cbiC
Precorrin-8X methylmutase CbiC/CobH.
 
 0.990
cobQ
Cobyrinic acid a,c-diamide synthase:Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.968
MMP0493
Probable metal chelatase.
 
 
 0.953
cbiL
Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.939
cbiT
SAM (and some other nucleotide) binding motif; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
  
 0.912
cbiF
Precorrin-4 C11-methyltransferase; Citation: Eur J Biochem 1998 Jun 1; 254(2):341-6.
  
 0.909
chiB
Cobalamin biosynthesis protein B; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.905
cbiJ
Precorrin-6x reductase CbiJ/CobK.
 
  
 0.804
cobS
Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.801
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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