| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMP1064 | dacZ | MMP1064 | MMP1479 | RNA-binding region RNP-1 (RNA recognition motif):Adenylate cyclase. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.765 |
| MMP1489 | dacZ | MMP1489 | MMP1479 | Inositol monophosphate related protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP (By similarity); In the N-terminal section; belongs to the inositol monophosphatase superfamily. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.841 |
| MMP1489 | hisC | MMP1489 | MMP1216 | Inositol monophosphate related protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP (By similarity); In the N-terminal section; belongs to the inositol monophosphatase superfamily. | Histidinol-phosphate aminotransferase; Citation: Conover RK, Doolittle WF. (1990) J Bacteriol 172:3244-9. | 0.789 |
| MMP1489 | rpl37ae | MMP1489 | MMP0249 | Inositol monophosphate related protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP (By similarity); In the N-terminal section; belongs to the inositol monophosphatase superfamily. | Ribosomal L37ae protein; Binds to the 23S rRNA. | 0.439 |
| cbiA | cbiA-2 | MMP1477 | MMP1478 | Cobyrinic acid a,c-diamide synthase. | Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA. | 0.999 |
| cbiA | dacZ | MMP1477 | MMP1479 | Cobyrinic acid a,c-diamide synthase. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.781 |
| cbiA | hisC | MMP1477 | MMP1216 | Cobyrinic acid a,c-diamide synthase. | Histidinol-phosphate aminotransferase; Citation: Conover RK, Doolittle WF. (1990) J Bacteriol 172:3244-9. | 0.414 |
| cbiA | leuC-2 | MMP1477 | MMP1480 | Cobyrinic acid a,c-diamide synthase. | Aconitase Family; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.530 |
| cbiA-2 | cbiA | MMP1478 | MMP1477 | Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA. | Cobyrinic acid a,c-diamide synthase. | 0.999 |
| cbiA-2 | dacZ | MMP1478 | MMP1479 | Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA. | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | 0.781 |
| cbiA-2 | hisC | MMP1478 | MMP1216 | Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA. | Histidinol-phosphate aminotransferase; Citation: Conover RK, Doolittle WF. (1990) J Bacteriol 172:3244-9. | 0.414 |
| cbiA-2 | leuC-2 | MMP1478 | MMP1480 | Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA. | Aconitase Family; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.569 |
| dacZ | MMP1064 | MMP1479 | MMP1064 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | RNA-binding region RNP-1 (RNA recognition motif):Adenylate cyclase. | 0.765 |
| dacZ | MMP1489 | MMP1479 | MMP1489 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Inositol monophosphate related protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP (By similarity); In the N-terminal section; belongs to the inositol monophosphatase superfamily. | 0.841 |
| dacZ | cbiA | MMP1479 | MMP1477 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Cobyrinic acid a,c-diamide synthase. | 0.781 |
| dacZ | cbiA-2 | MMP1479 | MMP1478 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA. | 0.781 |
| dacZ | glmM | MMP1479 | MMP1077 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Phosphoglucomutase/phosphomannomutase:Calcium- binding EF-hand; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. Also catalyzes the isomerization of glucose-1- phosphate to glucose-6-phosphate, but at a 5-fold lower rate. | 0.927 |
| dacZ | hisC | MMP1479 | MMP1216 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Histidinol-phosphate aminotransferase; Citation: Conover RK, Doolittle WF. (1990) J Bacteriol 172:3244-9. | 0.751 |
| dacZ | leuC-2 | MMP1479 | MMP1480 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Aconitase Family; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.879 |
| dacZ | manB | MMP1479 | MMP1372 | Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. | Phosphoglucomutase/phosphomannomutase; Belongs to the phosphohexose mutase family. | 0.810 |
