Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cbiMCobalamin biosynthesis protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (225 aa)    
Predicted Functional Partners:
cbiN
Conserved hypothetical protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
 
 
 0.999
cbiQ
Cobalt transport protein Q.
 
 0.999
cbiO
Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.997
MMP0886
Cobalt transport system permease related protein.
 
 
 0.953
MMP0889
Cobalamin (vitamin B12) biosynthesis CbiM protein.
  
  
0.931
MMP0888
Putative cobalt transport protein.
    
 0.845
cbiL
Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.780
cbiC
Precorrin-8X methylmutase CbiC/CobH.
  
  
 0.774
ehaP
Polyferredoxin; Citation: J. Mol. Evol. 1985 22: 20-31; J. Mol. Evol. 1989 29: 246-54.
     
 0.767
MMP0885
TPR repeat:ATP/GTP-binding site motif A (P-loop).
      
 0.760
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (16%) [HD]