STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gapNAldehyde dehydrogenase; Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. (465 aa)    
Predicted Functional Partners:
MMP0802
Iron-containing alcohol dehydrogenase.
 
 0.966
acsA
acetyl-CoA synthetase, AMP-forming; Citation: J Bact 173:6383.
  
 0.916
fucA
Class II aldolase/adducin, N-terminal; Involved in the biosynthesis of the coenzyme F420 which requires phospholactate produced via the aldol cleavage of L-fuculose 1-phosphate and the NAD(+)-dependent oxidation of (S)-lactaldehyde. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and S-lactaldehyde.
  
 
 0.902
ftsA-2
Coenzyme F390 synthetase.
  
 
 0.886
MMP0314
Coenzyme F390 synthetase.
  
 
 0.886
MMP0715
Coenzyme F390 synthetase II.
  
 
 0.886
pgi
Glucose-6-phosphate isomerase.
  
 
 0.858
MMP1274
acetyl-CoA synthetase, AMP-forming-related; Citation: J Bact 173:6383.
  
 0.842
tpiA
Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.
  
 
 0.840
MMP0566
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II related protein; Citation: Microbiology. 1997 Nov;143 (Pt 11):3443-50.
  
 
 0.838
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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