Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gapNAldehyde dehydrogenase; Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. (465 aa)    
Predicted Functional Partners:
MMP0802
Iron-containing alcohol dehydrogenase.
 
 0.972
hsp60
Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family.
  
 0.914
mdh
Malate dehydrogenase, MDHII (NADP+-dependent); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.911
MMP1605
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.903
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.892
tpiA
Triosephosphate isomerase; Belongs to the triosephosphate isomerase family.
  
 
 0.884
gap
Glyceraldehyde 3-phosphate dehydrogenase.
  
  
 0.879
MMP1585
Arginase; Belongs to the arginase family.
  
 0.846
pgi
Glucose-6-phosphate isomerase.
  
 
 0.841
lysC
Aspartate kinase; Citation: Tang G, Zhu-Shimoni JX, Amir R, Zchori IB, Galili G. (1997) Plant Mol Biol 34:287-93; Belongs to the aspartokinase family.
  
  
 0.836
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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