Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
agcSSodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. (453 aa)    
Predicted Functional Partners:
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. This organism is able to use both L- and D-alanine as a nitrogen source. May also prevent D-alanine from interfering with the use of L- alanine.
     
 0.842
ald
Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family.
     
 0.815
dacZ
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
  
  
 0.679
modA-3
Molybdenum ABC transporter, periplasmic molybdenum-binding protein; Citation: Self WT, et al. Res Mcirobial 2001;152(3-4): 311-21 Reck S, et al. JBC 1996;271(5): 2557-62.
   
  
 0.677
modA
Molybdenum ABC transporter, periplasmic molybdenum-binding protein; Citation: Self WT, et al. Res Microbiol 2001;152(3-4):311-21 Reck S, et al. JBC 1996;271(5): 2557-62.
      
 0.650
hpt
Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
     
 0.643
pheT
Phenylalanyl-tRNA synthetase beta subunit.
     
 0.643
modC-2
Molybdenum transport ATP-binding protein modC; Citation: Maupin-Furlow JA, et al. JBC 1995; 177(17): 4851-62 Rech S, et al. JBC 1996; 271(5): 2557-62.
      
 0.631
MMP1611
Conserved hypothetical protein.
      
 0.631
gatA
Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
  
  
 0.602
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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