STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
agcSSodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. (453 aa)    
Predicted Functional Partners:
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. This organism is able to use both L- and D-alanine as a nitrogen source. May also prevent D-alanine from interfering with the use of L- alanine.
     
 0.862
ald
Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family.
     
 0.833
dacZ
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
  
  
 0.681
modA-3
Molybdenum ABC transporter, periplasmic molybdenum-binding protein; Citation: Self WT, et al. Res Mcirobial 2001;152(3-4): 311-21 Reck S, et al. JBC 1996;271(5): 2557-62.
   
  
 0.673
modA
Molybdenum ABC transporter, periplasmic molybdenum-binding protein; Citation: Self WT, et al. Res Microbiol 2001;152(3-4):311-21 Reck S, et al. JBC 1996;271(5): 2557-62.
      
 0.662
pheT
Phenylalanyl-tRNA synthetase beta subunit.
     
 0.659
hpt
Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
     
 0.658
MMP1611
Conserved hypothetical protein.
      
 0.646
modC-2
Molybdenum transport ATP-binding protein modC; Citation: Maupin-Furlow JA, et al. JBC 1995; 177(17): 4851-62 Rech S, et al. JBC 1996; 271(5): 2557-62.
      
 0.644
amtB
Ammonia transporter.
  
  
 0.621
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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