node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMP0865 | ald | MMP0865 | MMP1513 | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | 0.523 |
MMP1137 | ald | MMP1137 | MMP1513 | Lrp-Like Transcriptional regulatory proteins, AsnC family; Citation: Dahlke I, Thomm M. (2002) Nucleic Acids Res. 30:701-10. | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | 0.530 |
MMP1137 | glnA | MMP1137 | MMP1206 | Lrp-Like Transcriptional regulatory proteins, AsnC family; Citation: Dahlke I, Thomm M. (2002) Nucleic Acids Res. 30:701-10. | Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. | 0.528 |
MMP1137 | trxB | MMP1137 | MMP0959 | Lrp-Like Transcriptional regulatory proteins, AsnC family; Citation: Dahlke I, Thomm M. (2002) Nucleic Acids Res. 30:701-10. | Thioredoxin reductase. | 0.426 |
agcS | ald | MMP1511 | MMP1513 | Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | 0.833 |
agcS | alr | MMP1511 | MMP1512 | Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. This organism is able to use both L- and D-alanine as a nitrogen source. May also prevent D-alanine from interfering with the use of L- alanine. | 0.862 |
agcS | glnA | MMP1511 | MMP1206 | Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. | Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. | 0.563 |
agcS | hpt | MMP1511 | MMP0145 | Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. | Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.658 |
agcS | nrpR | MMP1511 | MMP0607 | Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. | Transcriptional repressor of nif and glnA operons; Transcriptional repressor of nitrogen fixation and assimilation genes. Binds to two tandem operators in the glnA and nif promoters, thereby blocking transcription of the genes. | 0.493 |
agcS | upp | MMP1511 | MMP0680 | Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. | Uracil Phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate; Belongs to the UPRTase family. | 0.530 |
ald | MMP0865 | MMP1513 | MMP0865 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Adenosylmethionine---8-amino-7-oxononanoate aminotransferase; Citation: Kiyasu T, Nagahashi Y, Hoshino T. (2001) Gene 265:103-13; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.523 |
ald | MMP1137 | MMP1513 | MMP1137 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Lrp-Like Transcriptional regulatory proteins, AsnC family; Citation: Dahlke I, Thomm M. (2002) Nucleic Acids Res. 30:701-10. | 0.530 |
ald | agcS | MMP1513 | MMP1511 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Sodium:alanine symporter; Probably functions as a sodium/L- and D-alanine symporter for alanine uptake. | 0.833 |
ald | alr | MMP1513 | MMP1512 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. This organism is able to use both L- and D-alanine as a nitrogen source. May also prevent D-alanine from interfering with the use of L- alanine. | 0.996 |
ald | glnA | MMP1513 | MMP1206 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. | 0.483 |
ald | hpt | MMP1513 | MMP0145 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.671 |
ald | nrpR | MMP1513 | MMP0607 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Transcriptional repressor of nif and glnA operons; Transcriptional repressor of nitrogen fixation and assimilation genes. Binds to two tandem operators in the glnA and nif promoters, thereby blocking transcription of the genes. | 0.515 |
ald | pyrG | MMP1513 | MMP0893 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.453 |
ald | trxB | MMP1513 | MMP0959 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Thioredoxin reductase. | 0.488 |
ald | upp | MMP1513 | MMP0680 | Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle. Belongs to the AlaDH/PNT family. | Uracil Phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate; Belongs to the UPRTase family. | 0.506 |