STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
MMP1520Hydrogenase nickel incorporation protein HypB; ATP/GTP-binding site motif A (P-loop):HypB/UreG, nucleotide-binding:Hydrogenase accessory protein HypB. (224 aa)    
Predicted Functional Partners:
hypA
Hydrogenase accessory protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.995
ehbN
Energy conserving hydrogenase B large subunit; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43.
  
 
 0.881
hypD
Hydrogenase expression/formation protein.
 
  
 0.879
ehaO
Energy conserving hydrogenase A large subunit; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43.
   
 
 0.872
slyD
Peptidylprolyl isomerase, FKBP-type.
   
 
 0.868
MMP1190
Peptidylprolyl isomerase, FKBP-type.
   
 
 0.868
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
   
  
 0.867
MMP1330
Hydrogenase expression/formation protein (HUPF/HYPC).
 
  
 0.842
MMP0140
Conserved hypothetical protein; HypF family; Citation: Mol. Microbiol. 8 (3); 471-481 (1993).
 
  
 0.770
nifH-2
NifH/frxC family:ATP/GTP-binding site motif A (P-loop); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
     
 0.657
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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