Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1521Conserved hypothetical archaeal protein. (142 aa)    
Predicted Functional Partners:
MMP1522
Conserved hypothetical archaeal protein.
  
    0.818
mdh
Malate dehydrogenase, MDHII (NADP+-dependent); Catalyzes the reversible oxidation of malate to oxaloacetate.
       0.698
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
       0.685
secF
SecD/SecF/SecDF export membrane protein; Involved in protein export.
  
    0.630
secD
SecD/SecF/SecDF export membrane protein; Involved in protein export.
       0.627
cofG
FO synthase, subunit CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
       0.620
MMP1525
Modulator of DNA gyrase.
       0.437
rncS
Ribonuclease III family:Double-stranded RNA binding (DsRBD) domain.
  
    0.415
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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