Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
secFSecD/SecF/SecDF export membrane protein; Involved in protein export. (281 aa)    
Predicted Functional Partners:
secD
SecD/SecF/SecDF export membrane protein; Involved in protein export.
 
 0.999
atpC
A1A0 ATPase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
    0.707
hat
Histone acetyltransferase.
       0.687
MMP1522
Conserved hypothetical archaeal protein.
 
    0.683
trkA
Trk system potassium uptake protein A; Citation: Macario, A.J.L., Dugan, C.B., and Conway de Macario, E. 1216:495-498,1994.
 
   
 0.673
speH
S-adenosylmethionine decarboxylase related; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
  
    0.632
MMP1521
Conserved hypothetical archaeal protein.
  
    0.630
atpE
A1A0 ATPase, subunit IE; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.616
atpF
A1A0 ATPase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.616
MMP0387
Microsomal signal peptidase 21 KD subunit; Citation: J. Biol. Chem. 265:9512.
  
  
 0.610
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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