Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP1531Conserved hypothetical protein. (323 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
       0.889
MMP1530
Conserved hypothetical protein.
  
    0.810
pheA
Prephenate dehydratase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73.
  
    0.805
MMP1529
Conserved hypothetical archaeal protein.
       0.790
MMP0658
MoaA/nifB/pqqE family.
       0.689
MMP1346
Basic helix-loop-helix dimerization domain bHLH.
       0.675
MMP0143
Conserved hypothetical protein.
       0.616
dapL
Aminotransferase (subgroup I); Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
  
    0.566
MMP1593
Conserved hypothetical protein.
  
    0.517
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
       0.479
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (22%) [HD]