Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1539Conserved hypothetical protein. (186 aa)    
Predicted Functional Partners:
MMP1540
Conserved hypothetical Archael protein.
 
    0.997
MMP1537
Cytochrome c heme-binding site.
 
    0.929
MMP1538
Predicted transporter component.
 
    0.927
MMP0114
Conserved hypothetical protein.
  
    0.741
MMP0829
Coenzyme B12-binding:Cobalamin-dependent methionine synthase, B12-binding.
   
    0.737
mtaA-2
Uroporphyrinogen decarboxylase (URO-D).
   
    0.666
mtbC
Coenzyme B12-binding:Cobalamin-dependent methionine synthase, B12-binding.
   
    0.606
mtbA
Uroporphyrinogen decarboxylase (URO-D).
   
    0.584
vhcA
Coenzyme F420-non-reducing hydrogenase subunit alpha; Selenium independent; Citation: Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
    0.477
frcD
Coenzyme F420-reducing hydrogenase subunit delta; Cytoplasmic, selenium independent; Citation: Muth, E. et al. 1987. Eur. J. Biochem. 169:571-7. Rossmann, R. et al. 1995. Eur. J. Biochem. 227:545-50. Halboth,S., Klein,A.
  
    0.470
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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