Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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mcrAMethyl-coenzyme M reductase I, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (553 aa)    
Predicted Functional Partners:
mcrB
Methyl-coenzyme M reductase I, beta subunit; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
  
 0.999
mcrD
Methyl-coenzyme M reductase I, protein D; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
  
 0.999
mcrC
Methyl coenzyme M reductase I, protein C; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
  
 0.999
mcrG
Methyl-coenzyme M reductase I, gamma subunit; Citation: J. Bacterio. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
  
 0.999
atwA
Methyl coenzyme M reductase, component A2; Citation: J. Bact. 1993 175: 3196-3203.
   
 0.991
mtrH
N5-methyltetrahydromethanopterin: methyltransferase, subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
  
 
 0.985
MMP1554
Conserved hypothetical archaeal protein.
  
 
 0.970
mtrA
N5-methyltetrahydromethanopterin: methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
  
 
 0.960
or900
N5-methyltetrahydromethanopterin: methyltransferase, subunit A and F related protein; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
  
 
 0.951
mtrE
N5-methyltetrahydromethanopterin: methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
 
 0.950
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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