Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1581Putative DNA helicase. (633 aa)    
Predicted Functional Partners:
MMP1642
ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain.
  
 0.909
MMP0431
Rhodopsin-like GPCR superfamily:Beta-lactamase-like.
  
 0.868
MMP1381
Beta-lactamase-like:ATP/GTP-binding site motif A (P-loop).
  
 0.868
rpl3
LSU Ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 0.848
rpl14e
KOW motif; Belongs to the eukaryotic ribosomal protein eL14 family.
    
 0.822
aIF2-2
Translation initiation factor aIF-2, subunit alpha; Citation: Proc. Natl. Acad. Sci. USA 1998, 95: 3726-3730.
   
 
 0.808
rps3ae
SSU ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.789
hsp60
Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family.
  
 
 0.781
rpl7ae
Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity.
    
 0.759
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.753
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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