STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serAD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (523 aa)    
Predicted Functional Partners:
apgM
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.916
MMP0112
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2; Citation: FEBS Lett. 517:190-194(2002).
    
 0.911
MMP0598
Archaeal phosphoglycerate mutase-related; Citation: FEBS Lett. 517:190-194(2002).
    
 0.911
rplV
LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
 
 0.899
rpl13
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.897
rpl10e
Ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family.
  
 
 0.889
aspC
Aspartate aminotransferase; Citation: Tanaka T, Yamamoto S, Moriya T, Taniguchi M, Hayashi H, Kagamiyama H, Oi S. (1994) J Biochem (Tokyo) 115:309-17.
 
 
 0.879
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
 
 0.876
rpsI
SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.875
rps15
Probable SSU ribosomal protein S15P/S13E.
  
   0.872
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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