STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trkATrk system potassium uptake protein A; Citation: Macario, A.J.L., Dugan, C.B., and Conway de Macario, E. 1216:495-498,1994. (221 aa)    
Predicted Functional Partners:
MMP1430
Putative TRK system cation (K+) uptake protein; Citation: J Bacteriol. 1995 Apr;177(7):1908-10; Microbiol. 1998 144:2281-2289.
 
 
 0.994
MMP1598
Conserved hypothetical protein.
  
    0.966
moaE
Molybdopterin biosynthesis MoaE.
  
    0.923
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
 0.894
MMP0154
Conserved hypothetical archaeal protein; Belongs to the UPF0288 family.
   
    0.888
hemD
Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.878
aroA-2
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH) (Probable). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids and which is also a precursor for the biosynthesis of p-aminobenzoic acid (PABA) in M.maripaludis. Does not posses [...]
  
  
 0.878
MMP1240
Conserved hypothetical protein; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
   
    0.852
MMP0002
L-seryl-tRNA selenium transferase related protein.
  
    0.843
trpS
Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp).
 
  
 0.728
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.