STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP1606Flavoprotein:DNA/pantothenate metabolism flavoprotein. (396 aa)    
Predicted Functional Partners:
MMP1306
Conserved hypothetical protein.
 
  
 0.993
MMP0398
Conserved hypothetical archaeal protein.
 
  
 0.938
coaD
4'-phosphopantetheine adenylyltransferase.
    
 0.917
MMP1072
Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9.
 
 0.911
MMP1581
Putative DNA helicase.
  
 
 0.874
MMP1428
Hypothetical protein.
       0.827
MMP1468
Conserved hypothetical protein; Catalyzes the cleavage of L-cysteine to form 2-aminoprop-2- enoate and sulfide. The former then spontaneously hydrolyzes to pyruvate and NH(3). May be responsible for the production of sulfide required for the biosynthesis of iron-sulfur centers in this archaea.
     
  0.800
nadX
Protein of unknown function DUF108; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
       0.794
MMP1607
Protein of unknown function DUF99; Belongs to the UPF0215 family.
  
    0.767
MMP1605
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
    0.729
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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