Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP1634Protein of unknown function UPF0033:DsrE-like protein. (286 aa)    
Predicted Functional Partners:
MMP1633
Conserved hypothetical archaeal protein.
  
  
 0.997
MMP1635
Thioredoxin:Glutaredoxin:Thioredoxins/glutaredox in.
  
  
 0.857
MMP1190
Peptidylprolyl isomerase, FKBP-type.
      
 0.773
atpK
A1A0 ATPase, subunit K; Citation: Extremophiles 7:249.
  
   
 0.707
rpsI
SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family.
     
 0.642
psmA
Proteasome, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
      
 0.622
pfdB
Prefoldin beta subunit (GimC beta subunit); Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
      
 0.596
MMP0038
Conserved hypothetical protein.
 
    0.579
MMP0033
LysR family member; Contains a helix-turn-helix domain; Citation: Mol. Cell (2000) 6: 637-648. Nuc. Acids Res. (1999) 27: 4658-4670.
 
  
 0.523
MMP0308
Conserved hypothetical archaeal protein.
     
 0.515
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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