STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP1681Phosphoadenosine phosphosulfate reductase. (428 aa)    
Predicted Functional Partners:
cobA
uroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family.
 
  
 0.815
fruB
Coenzyme F420-reducing hydrogenase subunit beta; Membrane-bound, selenium dependent; Citation: Brodersen, J. et al. 1999. Arch. Microbiol. 171:115-21. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224.
     
 0.731
recJ
Single stranded DNA-specific exonuclease; Citation: J. Bacteriol. 182 (3), 607-612 (2000).
  
  
 0.728
hcp
Prismane; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.720
modB-2
Molybdenum transport system permease protein, modB RELATED; Citation: Self, W.T., et al. Res. Microbial. 2001(152): 311-321 Wang, SZ. et al. Biochem and Biophys Res Comm. 1990(169): 1122-1128.
  
  
 0.670
MMP1519
Anion transport system permease protein.
  
  
 0.670
MMP1650
Probable amino acid ABC transporter, periplasmic component.
  
  
 0.670
MMP0089
Conserved hypothetical protein.
 
  
 0.615
cbiX(s)
Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
  
  
 0.574
cbiF
Precorrin-4 C11-methyltransferase; Citation: Eur J Biochem 1998 Jun 1; 254(2):341-6.
 
    0.542
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.