STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comESulfopyruvate decarboxylase subunit beta; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde. (185 aa)    
Predicted Functional Partners:
comD
Sulfopyruvate decarboxylase subunit alpha; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde; Belongs to the ComD family.
 
 0.999
comC
L-sulfolactate dehydrogenase/(S)-hydroxyglutaric acid dehydrogenase; Citation: J. Bacteriol. 182:3688-3692(2000).
    
 0.982
comB
2-phosphosulfolactate phosphatase; Citation: Eur. J. Biochem. 268:5176-5188(2001).
      
 0.802
MMP1690
Similar to phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Belongs to the HisA/HisF family.
  
    0.793
mcrC
Methyl coenzyme M reductase I, protein C; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
      
 0.746
MMP0141
Conserved archaeal protein; Probable Zn finger protein; Prokaryotic DNA topoisomerase I-related (C-term).
  
    0.701
MMP0142
Thiamine pyrophosphate dependent enzyme related to acetolactate synthase; Citation: Bowen T.L. et al, Gene 188, 77 (1997); Belongs to the TPP enzyme family.
     
 0.689
comA
(2R)-phospho-3-sulfolactate synthase; Citation: J. Biol. Chem. 277:13421-13429(2002).
  
  
 0.684
MMP0535
Conserved hypothetical archaeal protein.
   
  
 0.670
MMP1688
Conserved hypothetical Archael protein.
   
  
 0.664
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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