Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1710Conserved hypothetical archeal protein. (198 aa)    
Predicted Functional Partners:
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
  
    0.967
pcnA
Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
  
 0.961
rps27e
SSU ribosomal protein S27E.
  
    0.947
MMP0547
RecJ related protein; Citation: J. Bact. (2000) 182: 607-612.
   
 
 0.798
recJ
Single stranded DNA-specific exonuclease; Citation: J. Bacteriol. 182 (3), 607-612 (2000).
   
 
 0.798
aIF2-2
Translation initiation factor aIF-2, subunit alpha; Citation: Proc. Natl. Acad. Sci. USA 1998, 95: 3726-3730.
  
    0.788
DP1
DNA polymerase, archaeal type II, small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
    
   0.785
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.769
MMP1078
Conserved Hypothetical Archael Protein.
   
 
 0.721
MMP1406
Protein translation factor SUI1 homolog; Citation: Auer,J., Spicker,G., Boeck,A.(1989) J. Mol. Biol. 209:21-36; Belongs to the SUI1 family.
  
  
 0.715
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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