node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSc0779 | RSc1602 | RSc0779 | RSc1602 | Putative thioredoxin protein. | Putative peptidase t1a, proteasome beta-subunit; protein. | 0.495 |
RSc0779 | dnaJ | RSc0779 | RSc2634 | Putative thioredoxin protein. | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.805 |
RSc0779 | dnaK | RSc0779 | RSc2635 | Putative thioredoxin protein. | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | 0.599 |
RSc0779 | grpE | RSc0779 | RSc2639 | Putative thioredoxin protein. | Probable protein grpe (hsp-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.856 |
RSc0779 | hslU | RSc0779 | RSc0042 | Putative thioredoxin protein. | Probable atp-dependent hsl protease atp-binding subunit hslu protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.881 |
RSc0779 | hslV | RSc0779 | RSc0043 | Putative thioredoxin protein. | Probable atp-dependent protease hslv protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.872 |
RSc0779 | htpG | RSc0779 | RSc0990 | Putative thioredoxin protein. | Probable chaperone protein htpg (heat shock protein htpg) (high temperatureprotein g); Molecular chaperone. Has ATPase activity. | 0.751 |
RSc0779 | lon | RSc0779 | RSc1713 | Putative thioredoxin protein. | Probable atp-dependent protease la protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.577 |
RSc0779 | mopA | RSc0779 | RSc0642 | Putative thioredoxin protein. | Probable 60 kda chaperonin (protein cpn60) (groel protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.807 |
RSc0779 | mopB | RSc0779 | RSc0641 | Putative thioredoxin protein. | Probable 10 kda chaperonin (protein cpn10) (groes protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.659 |
RSc1602 | RSc0779 | RSc1602 | RSc0779 | Putative peptidase t1a, proteasome beta-subunit; protein. | Putative thioredoxin protein. | 0.495 |
RSc1602 | dnaJ | RSc1602 | RSc2634 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.584 |
RSc1602 | dnaK | RSc1602 | RSc2635 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | 0.422 |
RSc1602 | grpE | RSc1602 | RSc2639 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable protein grpe (hsp-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.735 |
RSc1602 | hslU | RSc1602 | RSc0042 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable atp-dependent hsl protease atp-binding subunit hslu protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.957 |
RSc1602 | htpG | RSc1602 | RSc0990 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable chaperone protein htpg (heat shock protein htpg) (high temperatureprotein g); Molecular chaperone. Has ATPase activity. | 0.688 |
RSc1602 | lon | RSc1602 | RSc1713 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable atp-dependent protease la protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.709 |
RSc1602 | mopA | RSc1602 | RSc0642 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable 60 kda chaperonin (protein cpn60) (groel protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.734 |
RSc1602 | mopB | RSc1602 | RSc0641 | Putative peptidase t1a, proteasome beta-subunit; protein. | Probable 10 kda chaperonin (protein cpn10) (groes protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.716 |
dnaJ | RSc0779 | RSc2634 | RSc0779 | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | Putative thioredoxin protein. | 0.805 |