STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiDProbable bifunctional protein: hydroxy-phosphomethylpyrimidine kinase and hydroxy-methylpyrimidine kinase. (301 aa)    
Predicted Functional Partners:
thiE1
Probable thiamine-phosphate pyrophosphorylase protein.
 
 0.999
thiC
Thiamine biosynthesis protein thic thiamine biosynthesis; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 0.999
thiE2
Putative thiamine-phosphate pyrophosphorylase protein.
 
 
 0.993
thiG
Thiazole biosynthesis protein thig; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.981
thiS
Probable sulfur transfer protein this.
  
    0.879
thiF
Putative thif transmembrane protein.
  
 0.853
rhlE1
Probable atp-dependent rna helicase protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
 
   0.752
clpS
Hypothetical atp-dependent clp protease adaptor protein clps; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation.; Belongs to the ClpS family.
      
 0.740
RSc0101
Putative lipoprotein transmembrane.
       0.658
RSc0952
Putative atp-dependent rna helicase protein; Belongs to the DEAD box helicase family.
 
   0.632
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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