| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0869 | RSc3438 | RSc0869 | RSc3438 | Putative bacteriophage cytosine-specific methyltransferase protein. | Probable site-specific dna methylase protein. | 0.917 |
| RSc0869 | metK | RSc0869 | RSc0134 | Putative bacteriophage cytosine-specific methyltransferase protein. | S-adenosylmethionine synthetase (methionineadenosyltransferase) (adomet synthetase) (mat) protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.920 |
| RSc0869 | speH | RSc0869 | RSp1293 | Putative bacteriophage cytosine-specific methyltransferase protein. | Probable s-adenosylmethionine decarboxylase related transmembrane protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.900 |
| RSc3438 | RSc0869 | RSc3438 | RSc0869 | Probable site-specific dna methylase protein. | Putative bacteriophage cytosine-specific methyltransferase protein. | 0.917 |
| RSc3438 | metK | RSc3438 | RSc0134 | Probable site-specific dna methylase protein. | S-adenosylmethionine synthetase (methionineadenosyltransferase) (adomet synthetase) (mat) protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.920 |
| RSc3438 | speH | RSc3438 | RSp1293 | Probable site-specific dna methylase protein. | Probable s-adenosylmethionine decarboxylase related transmembrane protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.900 |
| RSp1583 | metE | RSp1583 | RSp0676 | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.920 |
| RSp1583 | metHa | RSp1583 | RSc0295 | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-b12 dependent isozyme) protein. | 0.917 |
| RSp1583 | metHb | RSp1583 | RSc0294 | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.918 |
| RSp1583 | metK | RSp1583 | RSc0134 | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | S-adenosylmethionine synthetase (methionineadenosyltransferase) (adomet synthetase) (mat) protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.928 |
| RSp1583 | metY | RSp1583 | RSc1562 | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | Probable o-acetylhomoserine (thiol)-lyase (methionine/homocysteine synthase) protein. | 0.917 |
| RSp1583 | tyrB | RSp1583 | RSc1010 | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | Probable aromatic-amino-acid aminotransferase protein. | 0.900 |
| metE | RSp1583 | RSp0676 | RSp1583 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | 0.920 |
| metE | metHa | RSp0676 | RSc0295 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-b12 dependent isozyme) protein. | 0.982 |
| metE | metHb | RSp0676 | RSc0294 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.962 |
| metE | metK | RSp0676 | RSc0134 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | S-adenosylmethionine synthetase (methionineadenosyltransferase) (adomet synthetase) (mat) protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.987 |
| metE | metY | RSp0676 | RSc1562 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Probable o-acetylhomoserine (thiol)-lyase (methionine/homocysteine synthase) protein. | 0.948 |
| metE | tyrB | RSp0676 | RSc1010 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Probable aromatic-amino-acid aminotransferase protein. | 0.905 |
| metHa | RSp1583 | RSc0295 | RSp1583 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-b12 dependent isozyme) protein. | Probable o-acetylhomoserine sulfhydrylase transmembrane protein. | 0.917 |
| metHa | metE | RSc0295 | RSp0676 | Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-b12 dependent isozyme) protein. | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.982 |
