STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFPutative methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1099 aa)    
Predicted Functional Partners:
RSc0283
Putative abc-type fe3+-hydroxamate transport system, periplasmic component abc transporter protein.
 
  
 0.866
lepB
Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family.
     
 0.752
RSc0474
Putative 3-hydroxyacyl-coa dehydrogenase oxidoreductase protein.
 
  
 0.721
RSc1999
Putative citrate lyase beta subunit protein; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.671
sucD
Probable succinyl-coa synthetase alpha chain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
   
 0.646
RSc1759
3-hydroxyacyl-CoA dehydrogenase; Probable trifunctonal: enoyl-coa hydratase and delta3-cis-delta2-trans-enoyl-coa isomerase and 3-hydroxyacyl-coa dehydrogenase oxidoreductase protein.
  
  
 0.634
RSc0265
Putative acetyl/propionyl-coa carboxylase, alpha subunit protein.
  
  
 0.631
fumA
Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.622
RSc2394
Probable abc-type transporter, periplasmic component abc transporter protein.
  
  
 0.622
RSc0269
Putative acetyl-coa carboxylase, carboxyltransferase (subunits alpha and beta) protein.
  
  
 0.619
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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