STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBProbable biotin synthase protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (360 aa)    
Predicted Functional Partners:
bioD
Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 0.999
bioA
Probable adenosylmethionine-8-amino-7-oxononanoate aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.997
birA
Putative bifunctional protein: biotin operon repressor and biotin--[acetyl-coa-carboxylase] synthetase.
  
 
 0.945
RSp1056
Probable beta-alanine--pyruvate aminotransferase (omega-amino acid--pyruvate aminotransferase) protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.930
RSc0082
Putative aminotransferase class-III; protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.905
bioF
Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 0.894
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.791
kbl
Probable 2-amino-3-ketobutyrate coenzyme a ligase protein; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
 0.784
RSc0269
Putative acetyl-coa carboxylase, carboxyltransferase (subunits alpha and beta) protein.
     
 0.708
thiC
Thiamine biosynthesis protein thic thiamine biosynthesis; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.663
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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