STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSc0277Probable carbonic anhydrase protein. (226 aa)    
Predicted Functional Partners:
RSp0113
Probable sulphate transporter; transmembrane protein.
  
 0.926
cynS
Putative remnant of cyanate lyase protein; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
  
 
 0.924
RSp0112
Putative carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
  
 
0.910
RSc1133
Putative carbonic anhydrase/acetyltransferase protein.
    
 
 0.759
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.736
apt
Probable adenine phosphoribosyltransferase (aprt) protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.587
RSc0279
Probable acyl-coa dehydrogenase oxidoreductase protein.
     
 0.470
gltB
Probable glutamate synthase (large subunit) oxidoreductase protein.
  
  
 0.402
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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