aceK protein (Ralstonia solanacearum) - STRING interaction network

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aceK

Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (608 aa)

Predicted Functional Partners:

icd

0.912

aceA

0.883

RSc0277

0.736

RSc0280

0.524

RSc0279

0.518

aceB

0.511

RSc0281

0.464

putA

0.429

Your Current Organism:

Ralstonia solanacearum

NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RSc0277	RSc0279	RSc0277	RSc0279	Probable carbonic anhydrase protein.	Probable acyl-coa dehydrogenase oxidoreductase protein.	0.470
RSc0277	aceK	RSc0277	RSc0278	Probable carbonic anhydrase protein.	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	0.736
RSc0279	RSc0277	RSc0279	RSc0277	Probable acyl-coa dehydrogenase oxidoreductase protein.	Probable carbonic anhydrase protein.	0.470
RSc0279	RSc0280	RSc0279	RSc0280	Probable acyl-coa dehydrogenase oxidoreductase protein.	Putative transcription regulator protein.	0.600
RSc0279	aceK	RSc0279	RSc0278	Probable acyl-coa dehydrogenase oxidoreductase protein.	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	0.518
RSc0280	RSc0279	RSc0280	RSc0279	Putative transcription regulator protein.	Probable acyl-coa dehydrogenase oxidoreductase protein.	0.600
RSc0280	RSc0281	RSc0280	RSc0281	Putative transcription regulator protein.	Putative beta-lactamase-like protein.	0.709
RSc0280	aceK	RSc0280	RSc0278	Putative transcription regulator protein.	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	0.524
RSc0281	RSc0280	RSc0281	RSc0280	Putative beta-lactamase-like protein.	Putative transcription regulator protein.	0.709
RSc0281	aceK	RSc0281	RSc0278	Putative beta-lactamase-like protein.	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	0.464
aceA	aceB	RSc1358	RSc1363	Probable isocitrate lyase protein.	Probable malate synthase a (msa or masy protein); Belongs to the malate synthase family.	0.999
aceA	aceK	RSc1358	RSc0278	Probable isocitrate lyase protein.	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	0.883
aceA	icd	RSc1358	RSc2490	Probable isocitrate lyase protein.	Probable isocitrate dehydrogenase [nadp] oxidoreductase protein.	0.670
aceA	putA	RSc1358	RSc3301	Probable isocitrate lyase protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.425
aceB	aceA	RSc1363	RSc1358	Probable malate synthase a (msa or masy protein); Belongs to the malate synthase family.	Probable isocitrate lyase protein.	0.999
aceB	aceK	RSc1363	RSc0278	Probable malate synthase a (msa or masy protein); Belongs to the malate synthase family.	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	0.511
aceB	icd	RSc1363	RSc2490	Probable malate synthase a (msa or masy protein); Belongs to the malate synthase family.	Probable isocitrate dehydrogenase [nadp] oxidoreductase protein.	0.811
aceK	RSc0277	RSc0278	RSc0277	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	Probable carbonic anhydrase protein.	0.736
aceK	RSc0279	RSc0278	RSc0279	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	Probable acyl-coa dehydrogenase oxidoreductase protein.	0.518
aceK	RSc0280	RSc0278	RSc0280	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.	Putative transcription regulator protein.	0.524

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