STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
coaXPutative transcription regulation accessory factor transcription regulator protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (295 aa)    
Predicted Functional Partners:
birA
Putative bifunctional protein: biotin operon repressor and biotin--[acetyl-coa-carboxylase] synthetase.
 
    0.979
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.968
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.963
dfp
Probable dna/pantothenate metabolism flavoprotein flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
    
 0.928
panD
Aspartate 1-decarboxylase alpha chain; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.801
RSc0310
Putative signal peptide protein.
       0.656
RSc0313
Putative abc-type transport system involved in resistance to organic solvents, permease component abc transporter protein.
 
     0.602
RSc0314
Probable cog1127, abc-type transport system involved in resistance to organic solvents, atpase component abc transporter protein.
       0.536
RSc0315
Probable abc-type transport system involved in resistance to organic solvents, periplasmic component abc transporter protein.
       0.535
RSc0316
Putative cog3218, abc-type uncharacterized transport system, auxiliary component abc transporter protein.
       0.524
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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