STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSc0346Putative pts system fructose subfamily IIa component; protein. (169 aa)    
Predicted Functional Partners:
pstH
Probable phosphocarrier protein hpr (phosphohistidinoprotein-hexose phosphotransferase).
 
 
 0.995
ptsI
Probable phosphoenolpyruvate-protein phosphotransferase transmembrane; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.928
RSc0691
Putative phosphomannomutase or phosphoglucomutase protein.
    
 0.906
scrK
Probable fructokinase protein.
    
 0.817
RSp1280
Probable sugar kinase protein.
    
 0.817
RSp1282
Probable pts system, fructose-specific eIIa/hpr/ei components protein.
 
 
 0.815
fruB
Probable multiphosphoryl transfer protein mtp.
 
 
 0.787
ptsN
Nitrogen PTS system EIIA component; Putative nitrogen regulatory IIa (enzyme IIa-ntr) (phosphotransferase enzyme II, a component) transcription regulator protein.
 
  
 0.772
hprK
Putative hpr kinase/phosphorylase (hprk/p) (hpr(ser)kinase/phosphorylase) protein; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
   
 0.760
gshB
Probable glutathione synthetase (glutathione synthase) (gshsynthetase) (gsh-s) (gshase) protein.
       0.722
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (22%) [HD]