STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCProbable dihydroorotase (dhoase) protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa)    
Predicted Functional Partners:
pyrD
Probable dihydroorotate dehydrogenase oxidoreductase protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.992
pyrB
Probable aspartate carbamoyltransferase (aspartatetranscarbamylase) (atcase) protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.974
pyrX
Probable dihydroorotase-like protein.
    
 0.924
RSc0488
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
       0.806
carB
Probable carbamoyl-phosphate synthase large chain (carbamoyl-phosphate synthetase ammonia chain) protein.
   
  
 0.725
ttuD2
Putative hydroxypyruvate reductase oxidoreductase protein.
       0.657
guaA
Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP.
   
  
 0.608
carA
Probable carbamoyl-phosphate synthase small chain (carbamoyl-phosphate synthetase glutamine chain) protein; Belongs to the CarA family.
   
  
 0.604
purF
Probable amidophosphoribosyltransferase protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.604
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
   
  
 0.581
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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