STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erpAConserved hypothetical protein; Required for insertion of 4Fe-4S clusters. (124 aa)    
Predicted Functional Partners:
iscU
Probable iron-binding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.903
hscA
Probable chaperone protein hsca homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
 
 
 0.851
hscB
Probable co-chaperone protein hscb homolog; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.; Belongs to the HscB family.
  
 
 0.759
iscS
Probable cysteine sulfinate desulfinase / cysteine desulfurase protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.671
RSc2904
Putative ipr004480 glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.670
RSp0173
Putative cysteine desulfurase (trna sulfurtransferase) protein.
 
  
 0.656
nuoI
Probable nadh dehydrogenaseI(chainI oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.605
RSc0493
Probable protein of unknown function duf583.
       0.567
RSc1782
Putative glycine cleavage t protein (aminomethyl transferase); Belongs to the GcvT family.
 
 
 0.543
mraW
Putative s-adenosyl-methyltransferase mraw protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
      
 0.540
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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