STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fisPutative fis-like dna-binding. transcription regulator protein; Belongs to the transcriptional regulatory Fis family. (77 aa)    
Predicted Functional Partners:
dusB
Putative trna-dihydrouridine synthase protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
  
  
 0.984
hfq
Putative hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
   
 0.731
purH
Probable bifunctional purine biosynthesis purh [includes:phosphoribosylaminoimidazolecarboxamide formyltransferase (aicar transformylase); imp cyclohydrolase (inosinicase) (imp synthetase) (atic)]. transmembrane protein.
  
    0.704
ihfA
Probable integration host factor alpha-subunit (ihf-alpha) protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
      
 0.694
polA
Probable dna polymeraseIprotein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
   0.675
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
     0.634
priB
Probable primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
   
    0.578
hexR
Putative transcription regulation repressor hexr transcription regulator protein.
      
 0.572
acpP
Probable acyl carrier protein 1 (acp 1); Carrier of the growing fatty acid chain in fatty acid biosynthesis.; Belongs to the acyl carrier protein (ACP) family.
      
 0.566
rpoE1
Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily.
      
 0.560
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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