STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pykA1Probable pyruvate kinase II protein; Belongs to the pyruvate kinase family. (479 aa)    
Predicted Functional Partners:
eno
Probable enolase (2-phosphoglycerate dehydratase) (2-phospho-d-glycerate hydro-lyase) protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.994
maeB1
Putative nadp-dependent malic enzyme oxidoreductase protein.
  
 0.963
maeB2
Putative nadp-dependent malic enzyme oxidoreductase protein.
  
 0.963
fbaA
Probable fructose-bisphosphate aldolase protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 0.960
pgk
Probable phosphoglycerate kinase protein; Belongs to the phosphoglycerate kinase family.
 
 
 0.955
pgi
Probable glucose-6-phosphate isomerase (gpi) (phosphoglucoseisomerase) (pgi) (phosphohexose isomerase) (phi). transmembrane protein.
 
 
 0.947
ldhA
Putative d-lactate dehydrogenase (d-ldh) oxidoreductase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.927
adk
Probable adenylate kinase (atp-amp transphosphorylase) protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.923
aceE
Probable pyruvate dehydrogenase e1 component oxidoreductase protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.922
rplB
Probable 50s ribosomal protein l2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.922
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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