STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdtAProbable 3-deoxy-d-manno-octulosonic-acid transferase transmembrane protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (438 aa)    
Predicted Functional Partners:
lpxK
Probable tetraacyldisaccharide 4'-kinase (lipid a 4'-kinase) protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.998
rfaC1
Probable lipopolysaccharide heptosyltransferase protein.
  
 0.993
kdsB
Probable 3-deoxy-manno-octulosonate (cmp-kdo synthetase)(cks) protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.986
rfaF
Probable adp-heptose--lipopolysaccharide heptosyltransferase II protein.
  
 0.984
RSc0136
Putative acyltransferase protein.
 
  
 0.969
rfaC2
Probable lipopolysaccharide heptosyltransferase protein.
 
  
 0.967
RSc0135
Putative acyltransferase transmembrane protein.
 
  
 0.963
waaL
Probable lipopolysaccharide o-antigen ligase transmembrane protein.
    
 0.923
RSc0413
Putative sugar isomerase (sis) protein; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.879
lpxD
Probable udp-3-o-[3-hydroxymyristoyl] glucosamine n-acyltransferase protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.873
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.