| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0707 | ubiD | RSc0707 | RSc0708 | Hypothetical protein; Miscellaneous; unknown. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.458 |
| RSc2434 | nagAa | RSc2434 | RSc1091 | Putative reductase oxidoreductase protein. | Probable ferredoxin oxidoreductase oxidoreductase protein. | 0.547 |
| RSc2434 | ubiD | RSc2434 | RSc0708 | Putative reductase oxidoreductase protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.597 |
| RSp0968 | RSp0969 | RSp0968 | RSp0969 | Putative lipid carrier protein sterol-binding protein. | Putative peptidase u32; protein. | 0.998 |
| RSp0968 | RSp0970 | RSp0968 | RSp0970 | Putative lipid carrier protein sterol-binding protein. | Probable peptidase u32; protein. | 0.997 |
| RSp0968 | ubiD | RSp0968 | RSc0708 | Putative lipid carrier protein sterol-binding protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.927 |
| RSp0968 | ubiE | RSp0968 | RSc0458 | Putative lipid carrier protein sterol-binding protein. | Probable ubiquinone/menaquinone biosynthesis methyltransferase ubie protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
| RSp0968 | ubiX | RSp0968 | RSc2905 | Putative lipid carrier protein sterol-binding protein. | Probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.922 |
| RSp0969 | RSp0968 | RSp0969 | RSp0968 | Putative peptidase u32; protein. | Putative lipid carrier protein sterol-binding protein. | 0.998 |
| RSp0969 | RSp0970 | RSp0969 | RSp0970 | Putative peptidase u32; protein. | Probable peptidase u32; protein. | 0.999 |
| RSp0969 | ubiD | RSp0969 | RSc0708 | Putative peptidase u32; protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.939 |
| RSp0969 | ubiE | RSp0969 | RSc0458 | Putative peptidase u32; protein. | Probable ubiquinone/menaquinone biosynthesis methyltransferase ubie protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
| RSp0969 | ubiX | RSp0969 | RSc2905 | Putative peptidase u32; protein. | Probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.930 |
| RSp0970 | RSp0968 | RSp0970 | RSp0968 | Probable peptidase u32; protein. | Putative lipid carrier protein sterol-binding protein. | 0.997 |
| RSp0970 | RSp0969 | RSp0970 | RSp0969 | Probable peptidase u32; protein. | Putative peptidase u32; protein. | 0.999 |
| RSp0970 | ubiD | RSp0970 | RSc0708 | Probable peptidase u32; protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.939 |
| RSp0970 | ubiE | RSp0970 | RSc0458 | Probable peptidase u32; protein. | Probable ubiquinone/menaquinone biosynthesis methyltransferase ubie protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
| RSp0970 | ubiX | RSp0970 | RSc2905 | Probable peptidase u32; protein. | Probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.925 |
| ispB | ubiA | RSc2823 | RSc2686 | Probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Probable 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.899 |
| ispB | ubiD | RSc2823 | RSc0708 | Probable octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.436 |