| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc1046 | kynA | RSc1046 | RSc0758 | Probable maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.587 |
| RSc1046 | kynA2 | RSc1046 | RSp0694 | Probable maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. | Putative tryptophan-2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.587 |
| RSc2196 | kynA | RSc2196 | RSc0758 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.587 |
| RSc2196 | kynA2 | RSc2196 | RSp0694 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Putative tryptophan-2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.587 |
| RSp0037 | kynA | RSp0037 | RSc0758 | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.521 |
| RSp0037 | kynU | RSp0037 | RSc0759 | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.663 |
| RSp1316 | hpd | RSp1316 | RSc3103 | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | 0.911 |
| RSp1316 | kynA | RSp1316 | RSc0758 | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.483 |
| hpd | RSp1316 | RSc3103 | RSp1316 | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | 0.911 |
| hpd | kynA | RSc3103 | RSc0758 | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.483 |
| kynA | RSc1046 | RSc0758 | RSc1046 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. | 0.587 |
| kynA | RSc2196 | RSc0758 | RSc2196 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.587 |
| kynA | RSp0037 | RSc0758 | RSp0037 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | 0.521 |
| kynA | RSp1316 | RSc0758 | RSp1316 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | 0.483 |
| kynA | hpd | RSc0758 | RSc3103 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. | 0.483 |
| kynA | kynA2 | RSc0758 | RSp0694 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Putative tryptophan-2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.925 |
| kynA | kynB | RSc0758 | RSc0760 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable kynurenine formidase protein; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.998 |
| kynA | kynU | RSc0758 | RSc0759 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.999 |
| kynA | trpA | RSc0758 | RSc1981 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable tryptophan synthase alpha chain protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.805 |
| kynA | trpB | RSc0758 | RSc1983 | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Probable tryptophan synthase beta chain protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.800 |
