| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc1826 | RSp0032 | RSc1826 | RSp0032 | Putative flavin oxidoreductase oxidoreductase protein. | Putative nadh:flavin oxidoreductases oxidoreductase protein. | 0.908 |
| RSc1826 | RSp0037 | RSc1826 | RSp0037 | Putative flavin oxidoreductase oxidoreductase protein. | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | 0.991 |
| RSc1826 | kynA | RSc1826 | RSc0758 | Putative flavin oxidoreductase oxidoreductase protein. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.453 |
| RSc1826 | kynA2 | RSc1826 | RSp0694 | Putative flavin oxidoreductase oxidoreductase protein. | Putative tryptophan-2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.444 |
| RSc1826 | kynU | RSc1826 | RSc0759 | Putative flavin oxidoreductase oxidoreductase protein. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.474 |
| RSc1835 | kynA | RSc1835 | RSc0758 | Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.510 |
| RSc1835 | kynA2 | RSc1835 | RSp0694 | Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. | Putative tryptophan-2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.510 |
| RSc1835 | kynU | RSc1835 | RSc0759 | Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.754 |
| RSp0032 | RSc1826 | RSp0032 | RSc1826 | Putative nadh:flavin oxidoreductases oxidoreductase protein. | Putative flavin oxidoreductase oxidoreductase protein. | 0.908 |
| RSp0032 | RSp0037 | RSp0032 | RSp0037 | Putative nadh:flavin oxidoreductases oxidoreductase protein. | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | 0.996 |
| RSp0032 | kynA | RSp0032 | RSc0758 | Putative nadh:flavin oxidoreductases oxidoreductase protein. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.466 |
| RSp0032 | kynA2 | RSp0032 | RSp0694 | Putative nadh:flavin oxidoreductases oxidoreductase protein. | Putative tryptophan-2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.453 |
| RSp0032 | kynU | RSp0032 | RSc0759 | Putative nadh:flavin oxidoreductases oxidoreductase protein. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.475 |
| RSp0037 | RSc1826 | RSp0037 | RSc1826 | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | Putative flavin oxidoreductase oxidoreductase protein. | 0.991 |
| RSp0037 | RSp0032 | RSp0037 | RSp0032 | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | Putative nadh:flavin oxidoreductases oxidoreductase protein. | 0.996 |
| RSp0037 | kynA | RSp0037 | RSc0758 | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | Probable tryptophan 2,3-dioxygenase oxidoreductase protein; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.488 |
| RSp0037 | kynU | RSp0037 | RSc0759 | Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.623 |
| hmgA | kynU | RSp0691 | RSc0759 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.522 |
| katE | katGb | RSp1581 | RSc0775 | Probable catalase hydroperoxidase hpII oxidoreductase protein; Belongs to the catalase family. | Probable peroxidase/catalase (cata) oxidoreductase protein; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.952 |
| katE | kynU | RSp1581 | RSc0759 | Probable catalase hydroperoxidase hpII oxidoreductase protein; Belongs to the catalase family. | Probable kynureninase protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.905 |