node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSc0768 | pdxH1 | RSc0768 | RSc0767 | Hypothetical protein; Miscellaneous; unknown. | Probable pyridoxamine 5'-phosphate oxidase (pnp/pmp oxidase) oxidoreductase protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.569 |
bioD | bioF | RSc1479 | RSc1478 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.992 |
bioD | cbiD | RSc1479 | RSp0622 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Putative cobalt-precorrin-6a synthase [deacetylating]. transmembrane protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.625 |
bioD | hemC | RSc1479 | RSc2357 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.623 |
bioD | nadC | RSc1479 | RSc2448 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Probable nicotinate-nucleotide pyrophosphorylase (carboxylating) quinolinate phosphoribosyltransferase (decarboxylating) protein; Belongs to the NadC/ModD family. | 0.746 |
bioD | panC | RSc1479 | RSc2387 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.717 |
bioD | pdxH1 | RSc1479 | RSc0767 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Probable pyridoxamine 5'-phosphate oxidase (pnp/pmp oxidase) oxidoreductase protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.564 |
bioD | pdxH2 | RSc1479 | RSp0678 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Probable pyridoxamine 5'-phosphate oxidase (pnp/pmp oxidase) oxidoreductase protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.557 |
bioD | ribH | RSc1479 | RSc0712 | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.721 |
bioF | bioD | RSc1478 | RSc1479 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.992 |
bioF | cbiD | RSc1478 | RSp0622 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Putative cobalt-precorrin-6a synthase [deacetylating]. transmembrane protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.700 |
bioF | hemC | RSc1478 | RSc2357 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.666 |
bioF | nadC | RSc1478 | RSc2448 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Probable nicotinate-nucleotide pyrophosphorylase (carboxylating) quinolinate phosphoribosyltransferase (decarboxylating) protein; Belongs to the NadC/ModD family. | 0.691 |
bioF | panC | RSc1478 | RSc2387 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.641 |
bioF | pdxH1 | RSc1478 | RSc0767 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Probable pyridoxamine 5'-phosphate oxidase (pnp/pmp oxidase) oxidoreductase protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.642 |
bioF | pdxH2 | RSc1478 | RSp0678 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Probable pyridoxamine 5'-phosphate oxidase (pnp/pmp oxidase) oxidoreductase protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.568 |
bioF | pdxJ | RSc1478 | RSc1066 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Probable pyridoxal phosphate biosynthetic protein pdxj (pnp synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.590 |
bioF | ribH | RSc1478 | RSc0712 | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.684 |
cbiD | bioD | RSp0622 | RSc1479 | Putative cobalt-precorrin-6a synthase [deacetylating]. transmembrane protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Probable dethiobiotin synthetase (dethiobiotin synthase) (dtbsynthetase) (dtbs) protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.625 |
cbiD | bioF | RSp0622 | RSc1478 | Putative cobalt-precorrin-6a synthase [deacetylating]. transmembrane protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Probable 8-amino-7-oxononanoate synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.700 |