| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0779 | RSc1139 | RSc0779 | RSc1139 | Putative thioredoxin protein. | Probable thioredoxin reductase oxidoreductase protein. | 0.788 |
| RSc0779 | RSp1137 | RSc0779 | RSp1137 | Putative thioredoxin protein. | Putative rhs-related transmembrane protein. | 0.796 |
| RSc0779 | dnaJ | RSc0779 | RSc2634 | Putative thioredoxin protein. | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.810 |
| RSc0779 | gor | RSc0779 | RSc0014 | Putative thioredoxin protein. | Probable glutathione reductase oxidoreductase protein. | 0.927 |
| RSc0779 | grpE | RSc0779 | RSc2639 | Putative thioredoxin protein. | Probable protein grpe (hsp-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.897 |
| RSc0779 | hslU | RSc0779 | RSc0042 | Putative thioredoxin protein. | Probable atp-dependent hsl protease atp-binding subunit hslu protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.866 |
| RSc0779 | hslV | RSc0779 | RSc0043 | Putative thioredoxin protein. | Probable atp-dependent protease hslv protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.875 |
| RSc0779 | mopA | RSc0779 | RSc0642 | Putative thioredoxin protein. | Probable 60 kda chaperonin (protein cpn60) (groel protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.905 |
| RSc0779 | nrdA | RSc0779 | RSc2805 | Putative thioredoxin protein. | Putative ribonucleoside reductase 1 (large chain) oxidoreductase protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.839 |
| RSc0779 | trxB | RSc0779 | RSc2342 | Putative thioredoxin protein. | Probable thioredoxin reductase oxidoreductase protein. | 0.901 |
| RSc1139 | RSc0779 | RSc1139 | RSc0779 | Probable thioredoxin reductase oxidoreductase protein. | Putative thioredoxin protein. | 0.788 |
| RSc1139 | trxB | RSc1139 | RSc2342 | Probable thioredoxin reductase oxidoreductase protein. | Probable thioredoxin reductase oxidoreductase protein. | 0.919 |
| RSp1137 | RSc0779 | RSp1137 | RSc0779 | Putative rhs-related transmembrane protein. | Putative thioredoxin protein. | 0.796 |
| dnaJ | RSc0779 | RSc2634 | RSc0779 | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | Putative thioredoxin protein. | 0.810 |
| dnaJ | grpE | RSc2634 | RSc2639 | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | Probable protein grpe (hsp-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Severa [...] | 0.998 |
| dnaJ | hslU | RSc2634 | RSc0042 | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | Probable atp-dependent hsl protease atp-binding subunit hslu protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.936 |
| dnaJ | hslV | RSc2634 | RSc0043 | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | Probable atp-dependent protease hslv protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.901 |
| dnaJ | mopA | RSc2634 | RSc0642 | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | Probable 60 kda chaperonin (protein cpn60) (groel protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.978 |
| dnaJ | nrdA | RSc2634 | RSc2805 | Probable chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | Putative ribonucleoside reductase 1 (large chain) oxidoreductase protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.487 |
| gor | RSc0779 | RSc0014 | RSc0779 | Probable glutathione reductase oxidoreductase protein. | Putative thioredoxin protein. | 0.927 |
