STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
RSc0802Putative membrane protease subunit, stomatin/prohibitin homolog transmembrane protein. (249 aa)    
Predicted Functional Partners:
RSc0803
Putative membrane-bound serine protease (clpp class) transmembrane protein.
 
    0.966
coxM
Probable cytochrome c oxidase polypeptide II (cytochrome bb3 subunit 2) transmembrane protein.
   
 
 0.790
hflB
Probable atp-dependent zinc metallopeptidase (cell division ftsh) transmembrane protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.739
RSc2119
Probable chlorohydrolase protein.
      0.568
RSc0804
Probable transcription regulator protein; Belongs to the LysR transcriptional regulatory family.
  
    0.562
RSc1222
Putative membrane protease subunits, stomatin/prohibitin homologs transmembrane protein; HflC and HflK could encode or regulate a protease.
  
   
 0.560
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
    0.518
RSc0675
Cog1678, putative transcriptional regulator protein; Belongs to the UPF0301 (AlgH) family.
  
    0.470
RSc0388
Probable peptidase signal peptide protein; EC_number 3.4.99.-.
  
 0.462
RSc1422
Hypothetical transmembrane protein.
  
 
 0.459
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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