| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0897 | ubiG | RSc0897 | RSc0898 | Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.817 |
| RSc1425 | RSc2893 | RSc1425 | RSc2893 | Putative oligoketide cyclase/lipid transport protein. | Putative oxidoreductase protein. | 0.663 |
| RSc1425 | ubiA | RSc1425 | RSc2686 | Putative oligoketide cyclase/lipid transport protein. | Probable 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.462 |
| RSc1425 | ubiG | RSc1425 | RSc0898 | Putative oligoketide cyclase/lipid transport protein. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.697 |
| RSc1425 | ubiH | RSc1425 | RSc0508 | Putative oligoketide cyclase/lipid transport protein. | Probable 2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein. | 0.621 |
| RSc2893 | RSc1425 | RSc2893 | RSc1425 | Putative oxidoreductase protein. | Putative oligoketide cyclase/lipid transport protein. | 0.663 |
| RSc2893 | coq7 | RSc2893 | RSc2854 | Putative oxidoreductase protein. | Probable ipr011566 ubiquinone biosynthesis and related protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.459 |
| RSc2893 | ubiA | RSc2893 | RSc2686 | Putative oxidoreductase protein. | Probable 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.729 |
| RSc2893 | ubiG | RSc2893 | RSc0898 | Putative oxidoreductase protein. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.709 |
| RSp0597 | coq7 | RSp0597 | RSc2854 | Putative 3-demethylubiquinone-9 3-methyltransferase; protein. | Probable ipr011566 ubiquinone biosynthesis and related protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.900 |
| RSp0597 | ubiG | RSp0597 | RSc0898 | Putative 3-demethylubiquinone-9 3-methyltransferase; protein. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.908 |
| RSp0597 | ubiH | RSp0597 | RSc0508 | Putative 3-demethylubiquinone-9 3-methyltransferase; protein. | Probable 2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein. | 0.900 |
| cobT | queE | RSc2397 | RSc1449 | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | Probable organic radical activating enzyme protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.744 |
| cobT | queF | RSc2397 | RSc0448 | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | Putative gtp cyclohydrolaseI protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.829 |
| cobT | ubiG | RSc2397 | RSc0898 | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.756 |
| coq7 | RSc2893 | RSc2854 | RSc2893 | Probable ipr011566 ubiquinone biosynthesis and related protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Putative oxidoreductase protein. | 0.459 |
| coq7 | RSp0597 | RSc2854 | RSp0597 | Probable ipr011566 ubiquinone biosynthesis and related protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Putative 3-demethylubiquinone-9 3-methyltransferase; protein. | 0.900 |
| coq7 | ubiG | RSc2854 | RSc0898 | Probable ipr011566 ubiquinone biosynthesis and related protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.963 |
| coq7 | ubiH | RSc2854 | RSc0508 | Probable ipr011566 ubiquinone biosynthesis and related protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Probable 2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein. | 0.434 |
| queE | cobT | RSc1449 | RSc2397 | Probable organic radical activating enzyme protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.744 |