node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSc0309 | RSc0523 | RSc0309 | RSc0523 | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | Putative histidinol phosphatase or related phosphatase protein. | 0.992 |
RSc0309 | hldD | RSc0309 | RSc0915 | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.980 |
RSc0309 | rfaC1 | RSc0309 | RSc0692 | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | Probable lipopolysaccharide heptosyltransferase protein. | 0.805 |
RSc0309 | rfaC2 | RSc0309 | RSp0634 | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | Probable lipopolysaccharide heptosyltransferase protein. | 0.805 |
RSc0309 | rfaE | RSc0309 | RSc0914 | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | Probable adp-heptose synthase protein. | 0.982 |
RSc0309 | rfaF | RSc0309 | RSc0565 | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | Probable adp-heptose--lipopolysaccharide heptosyltransferase II protein. | 0.825 |
RSc0523 | RSc0309 | RSc0523 | RSc0309 | Putative histidinol phosphatase or related phosphatase protein. | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | 0.992 |
RSc0523 | hldD | RSc0523 | RSc0915 | Putative histidinol phosphatase or related phosphatase protein. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.750 |
RSc0523 | rfaC1 | RSc0523 | RSc0692 | Putative histidinol phosphatase or related phosphatase protein. | Probable lipopolysaccharide heptosyltransferase protein. | 0.785 |
RSc0523 | rfaC2 | RSc0523 | RSp0634 | Putative histidinol phosphatase or related phosphatase protein. | Probable lipopolysaccharide heptosyltransferase protein. | 0.775 |
RSc0523 | rfaE | RSc0523 | RSc0914 | Putative histidinol phosphatase or related phosphatase protein. | Probable adp-heptose synthase protein. | 0.982 |
RSc0523 | rfaF | RSc0523 | RSc0565 | Putative histidinol phosphatase or related phosphatase protein. | Probable adp-heptose--lipopolysaccharide heptosyltransferase II protein. | 0.950 |
RSc0911 | hldD | RSc0911 | RSc0915 | Probable transmembrane protein. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.629 |
RSc0911 | lapB | RSc0911 | RSc0912 | Probable transmembrane protein. | Hypothetical transmembrane protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.881 |
RSc0911 | rfaE | RSc0911 | RSc0914 | Probable transmembrane protein. | Probable adp-heptose synthase protein. | 0.629 |
RSc0911 | ugd | RSc0911 | RSc0913 | Probable transmembrane protein. | Probable udp-glucose 6-dehydrogenase (ugd) oxidoreductase protein. | 0.651 |
hldD | RSc0309 | RSc0915 | RSc0309 | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. | 0.980 |
hldD | RSc0523 | RSc0915 | RSc0523 | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Putative histidinol phosphatase or related phosphatase protein. | 0.750 |
hldD | RSc0911 | RSc0915 | RSc0911 | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Probable transmembrane protein. | 0.629 |
hldD | lapB | RSc0915 | RSc0912 | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Hypothetical transmembrane protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.639 |