STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (331 aa)    
Predicted Functional Partners:
RSc0309
Conserved hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
 
 
 0.980
rfaE
Probable adp-heptose synthase protein.
 
  
 0.959
ugd
Probable udp-glucose 6-dehydrogenase (ugd) oxidoreductase protein.
 
 
 0.891
rfaF
Probable adp-heptose--lipopolysaccharide heptosyltransferase II protein.
 
  
 0.833
rpsL
Probable 30s ribosomal protein s12; With S4 and S5 plays an important role in translational accuracy.
   
 0.766
rpsN
Probable 30s ribosomal protein s14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.; Belongs to the universal ribosomal protein uS14 family.
   
  0.765
rpsS
Probable 30s ribosomal protein s19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.765
rpsC
Probable 30s ribosomal protein s3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.; Belongs to the universal ribosomal protein uS3 family.
   
 0.759
rpsQ
Probable 30s ribosomal subunit protein s17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 0.754
rpsH
Probable 30s ribosomal protein s8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.; Belongs to the universal ribosomal protein uS8 family.
   
 0.752
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.